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Goserelin Acetate
Cat #
KTA-32
Introduction
Goserellin Acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Sequence
Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2 Acetate salt
MW
1269.43
Reference
A. Wells et al., Clin. Cancer Res., 8, 1251 (2002)
H. Lepor, Rev. Urol., 7 (Suppl. 5), S3 (2005)
A. Rody et al., Expert Rev. Anticancer Ther., 5, 591 (2005)
Merck Index, 14th ed., No. 4526, (2006)
M. Roach 3rd and A. Izaguirre, Expert Opin. Pharmacother., 8, 257 (2007)
R. M. Herrmann et al., Rad. Oncol., 2, 31 (2007)
Fields of application
Advanced hormone-dependent prostate cancer
Advanced hormone-dependent Breast cancer
Endometriosis
Uterine myoma
Use in reproductive medicine
Synonyms
(D-Ser(tBu)6,Azagly10)-LHRH
Structure
leuprorelin acetate manufacturer, leuprorelin acetate in korea, leuprolide acetate manufacturer, ganirelix acetate, desmopressin acetate
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